Lincomycin Hydrochloride: Clinical and Laboratory Studies

Lincomycin Hydrochloride: Clinical and Laboratory Studies.

Stability studies of lincomycin hydrochloride in aqueous solution and intravenous infusion fluids.

PURPOSE The purpose of this study was to evaluate the chemical stability of Lincocin(®) (lincomycin hydrochloride) in commonly used intravenous fluids at room temperature (25°C), at accelerated-degradation temperatures and in selected buffer solutions. MATERIALS AND METHODS The stability of Lincocin(®) injection (containing lincomycin 600 mg/2 mL as the hydrochloride) stored at 25°C±0.1°C in ...

Trimethoprim: laboratory and clinical studies.

Trimethoprim is a synthetic compound which arrests the step in bacterial purine synthesis immediately succeeding that interfered with by sulphonamides. Acting alone it inhibits the growth of a wide range of bacteria in generally much lower concentrations than sulphonamides. Its action with a sulphonamide is strongly synergic and bactericidal.Studies are described of suitable cultural conditions...

Case of Reiter's disease treated with lincomycin hydrochloride.

A 33-year-old labourer, with no previous history of articular disease, was admitted to hospital complaining of general malaise and pain and swelling of the ankles and feet. He had also developed a pustular eruption on the soles of his feet, but had not had diarrhoea, urethral discharge, or conjunctivitis. His last sexual contact was stated to be six months previously. On examination he was pale...

Cephalexin: clinical and laboratory studies.

Cephalexin, 7